Methaqualone poisoning with muscular hyperactivity necessitating the use of curare.

Sensitivity of Skeletal Muscle to Intra-arterial Acetylcholine in Normal and Myasthenic Man.

The weakness and fatigability of skeletal muscle in myasthenia gravis have been likened to similar phenomena which occur in curare poisoning. As the intensity of curarization increases, muscle groups weaken in a certain order. The same muscle groups are often affected in the same order as myasthenia gravis progresses. The mechanism of death by interference with respiration is often strikingly s...

Prevalence of Attention Deficit Hyperactivity Disorder in Adults Hospitalized in Toxicology Ward of Mashhad University of Medical Sciences with Alcohol Poisoning

Background: Attention Deficit Hyperactivity Disorder (ADHD) is a common psychiatric disorder among children and adolescents that can be continued into adulthood in 30 to 50% of cases. Adult ADHD disorder can affect the performance of an individual and may predispose to drug abuse, alcoholism, smoking, sexual offenses, violation of law, educational and other social problems. The coincidences of ...

[Morphological studies on modifications induced by curare poisoning in motor plaques].

Changing pattern of drugs used for self-poisoning.

In 1967-76 the annual number of admissions to a poisoning treatment centre rose from 964 to 2134. The proportion of admissions caused by taking barbiturate hypnotics and methaqualone fell considerably while that caused by taking benzodiazepines and tricyclic antidepressants increased. As a result the proportion of patients admitted unconscious fell from 23% to 15%. The declining contributions o...

Study of sensitivity to curare in certain neurological disorders using a regional technique.

A regional technique for the study of curare sensitivity has been applied to patients with Duchenne type muscular dystrophy, myotonic disorders, certain lower motor neurone disorders, to patients with weakness in the arm after hemiplegia, to patients with hyper-reflexia and hypertonia without weakness, and to Parkinsonism. In the dystrophy patients, sensitivity to curare differs from normal con...